Leadership Performance at Any Scale
AMD Instinct™ GPUs enable leadership performance for the data center, at any scale—from single-server solutions up to the world’s largest, Exascale-class supercomputers.
Enterprise AI, Ready Where you Are
AMD Instinct™ MI350P PCIe® cards are built to help Enterprises of all sizes and scales achieve AI performance within their existing infrastructure. Hear from AMD CVP, Suresh Andani, and AMD ecosystem partners about how AMD Instinct MI350P PCIe cards offer leadership performance with an open, enterprise-ready AI stack, simplifying deployment.
Hear From Our Software Partners
Meet the AMD Instinct™ MI350 Series GPUs
AMD Instinct™ MI350 Series GPUs
The AMD Instinct™ MI350 Series GPUs set a new standard for generative AI and high performance computing (HPC) in data centers. Built on the new cutting-edge 4th Gen AMD CDNA™ architecture, these GPUs deliver exceptional efficiency and performance for training massive AI models, high-speed inference, and complex HPC workloads like scientific simulations, data processing, and computational modeling.
New AMD Instinct™ MI350P PCIe® Card
The AMD Instinct MI350P PCIe card offers a practical path to scale generative AI workloads across industries with little to no infrastructure change. Built using 4th Gen AMD CDNA™ architecture, these PCIe-based cards deliver exceptional efficiency and performance for mainstream enterprise workloads with a robust full stack enterprise focused software stack to simplify deployment.
Under the Hood
AMD Instinct GPUs are built on AMD CDNA™ architecture, which offers Matrix Core Technologies and support for a broad range of datatype capabilities—from the highly efficient MXFP4 and MXFP6 (including INT8, OCP-FP8 and FP16/BF16 sparsity support for AI), to the most demanding FP64 for HPC.
Portfolio
AMD Instinct MI350 Series GPUs
AMD Instinct MI300 Series GPUs
AMD Instinct MI200 Series
Software
Cloud Access
Experience AMD Instinct GPUs in the Cloud
Support your AI, HPC, and software development needs with programs supported by leading cloud service providers.
Server Solutions
AMD Instinct GPU Partners and Server Solutions
AMD collaborates with leading Original Equipment Manufacturers (OEMs), and platform designers to offer a robust ecosystem of AMD Instinct GPU-powered solutions.
Powering the AI & HPC Software Ecosystem with AMD Instinct™ GPUs
At AMD, we believe that advancing AI and HPC requires deep collaboration. Our collaborators span the full spectrum of AI and HPC ecosystem—from model development and large-scale training, to simulation, scientific research, and real-time inference. Together, we power breakthroughs in fields ranging from artificial intelligence to computational fluid dynamics, weather modelling, and beyond.
Case Studies
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TensorWave: Reliable, Resilient, Cost-Optimized AI Cloud
TensorWave built an AMD Instinct™ GPU cloud delivering reliable, resilient AI infrastructure with up to 2x performance and 40–60% cost savings vs. alt…
May 06, 2026
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Maincode Builds An AI Factory for Australia with AMD
Maincode’s upcoming $30M MC-2 AI factory uses AMD Instinct™ MI355X GPUs to deliver sovereign, cost-efficient AI systems for Australian enterprises.
April 16, 2026
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Biznet Gio Scales Cloud Performance for AI Era with AMD
Biznet Gio improved cloud scalability and AI readiness with AMD EPYC™ Server CPUs, delivering better performance, cost efficiency, and energy savings.
March 03, 2026
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LiquidMetal AI Delivers Cost-Effective GenAI Performance with AMD
AMD Instinct™ MI325X GPUs on Vultr help LiquidMetal AI deliver cloud-scale inference with efficiency and reach
February 23, 2026
Resources
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Footnotes
- Top 500 list as of November, 2025 https://top500.org/lists/top500/list/2025/11
Footnotes
- Top 500 list as of November, 2025 https://top500.org/lists/top500/list/2025/11